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1

Cancer chemotherapy: A critical analysis of its 60 years of history

Darío Galmarini, Carlos M. Galmarini, Felipe C. Galmarini

Journal:

Critical Reviews in Oncology/Hematology

Year:

2012

Language:

english

File:

PDF, 1.04 MB

english, 2012

2

Mutational Targets in Colorectal Cancer Cells with Microsatellite Instability

Jacques Bertholon, Qing Wang, Carlos Maria Galmarini, Alain Puisieux

Journal:

Familial Cancer

Year:

2006

Language:

english

File:

PDF, 184 KB

english, 2006

3

Plocabulin, a novel tubulin-binding agent, inhibits angiogenesis by modulation of microtubule dynamics in endothelial cells

Galmarini, Carlos M., Martin, Maud, Bouchet, Benjamin Pierre, Guillen-Navarro, María José, Martínez-Diez, Marta, Martinez-Leal, Juan Fernando, Akhmanova, Anna, Aviles, Pablo

Journal:

Year:

2018

Language:

english

File:

PDF, 5.59 MB

english, 2018

4

Molecular basis of resistance to the microtubule-depolymerizing antitumor compound plocabulin

Pantazopoulou, Areti, Galmarini, Carlos María, Peñalva, Miguel A.

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 6.02 MB

english, 2018

5

Sensitization of ara-C-resistant lymphoma cells by a pronucleotide analogue

Carlos María Galmarini, Marilyn L. Clarke, Cheryl L. Santos, Lars Jordheim, Christian Perigaud, Gilles Gosselin, Emeline Cros, John R. Mackey, Charles Dumontet

Journal:

International Journal of Cancer

Year:

2003

Language:

english

File:

PDF, 158 KB

english, 2003

6

Expression of a non-functional p53 affects the sensitivity of cancer cells to gemcitabine

Carlos María Galmarini, Marilyn L. Clarke, Nicole Falette, Alain Puisieux, John R. Mackey, Charles Dumontet

Journal:

International Journal of Cancer

Year:

2002

Language:

english

File:

PDF, 228 KB

english, 2002

7

A p21/WAF1 mutation favors the appearance of drug resistance to paclitaxel in human noncancerous epithelial mammary cells

Carlos María Galmarini, Benjamin Pierre Bouchet, Carole Audoynaud, Christelle Lamblot, Nicole Falette, Jacques Bertholon, Qing Wang, Anne Beghin, Charles Dumontet, Alain Puisieux

Journal:

International Journal of Cancer

Year:

2006

Language:

english

File:

PDF, 490 KB

english, 2006

8

Efficient overcoming of drug resistance to anticancer nucleoside analogs by nanodelivery of active phosphorylated drugs

Carlos M. Galmarini, Galya Warren, Madapathage T. Senanayake, Serguei V. Vinogradov

Journal:

International Journal of Pharmaceutics

Year:

2010

Language:

english

File:

PDF, 343 KB

english, 2010

9

Synthesis and antiproliferative activity of clausine E, mukonine, and koenoline bioisosteres

François Liger, Florence Popowycz, Thierry Besson, Laurent Picot, Carlos M. Galmarini, Benoît Joseph

Journal:

Bioorganic & Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 144 KB

english, 2007

10

p53 as a target for anti-cancer drug development

Benjamin Pierre Bouchet, Claude Caron de Fromentel, Alain Puisieux, Carlos María Galmarini

Journal:

Critical Reviews in Oncology/Hematology

Year:

2006

Language:

english

File:

PDF, 329 KB

english, 2006

11

What does over-expression of cN-II enzyme signify in haematological malignancies?

Carlos M. Galmarini

Journal:

Leukemia Research

Year:

2007

Language:

english

File:

PDF, 86 KB

english, 2007

12

Does p16ink4a expression increase with the number of cell doublings in normal and malignant lymphocytes?

Amel Chebel, Wei-Wen Chien, Luc-Marie Gerland, Yahia Mekki, Yves Bertrand, Patrick Ffrench, Carlos Maria Galmarini, Martine Ffrench

Journal:

Leukemia Research

Year:

2007

Language:

english

File:

PDF, 627 KB

english, 2007

13

Potential mechanisms of resistance to cytarabine in AML patients

Carlos M. Galmarini, Xavier Thomas, Fabien Calvo, Philippe Rousselot, Assia El Jafaari, Emeline Cros, Charles Dumontet

Journal:

Leukemia Research

Year:

2002

Language:

english

File:

PDF, 184 KB

english, 2002

14

In vivo mechanisms of resistance to cytarabine in acute myeloid leukaemia

Carlos M. Galmarini, Xavier Thomas, Fabien Calvo, Philippe Rousselot, Muriel Rabilloud, Assia El Jaffari, Emeline Cros, Charles Dumontet

Journal:

British Journal of Haematology

Year:

2002

Language:

english

File:

PDF, 263 KB

english, 2002

15

Deoxycytidine kinase and cN-II nucleotidase expression in blast cells predict survival in acute myeloid leukaemia patients treated with cytarabine

Carlos María Galmarini, Xavier Thomas, Kathryn Graham, Assia El Jafaari, Emeline Cros, Lars Jordheim, John R. Mackey, Charles Dumontet

Journal:

British Journal of Haematology

Year:

2003

Language:

english

File:

PDF, 237 KB

english, 2003

16

Resistance to gemcitabine in a human follicular lymphoma cell line is due to partial deletion of the deoxycytidine kinase gene

Carlos María Galmarini, Marilyn L Clarke, Lars Jordheim, Cheryl L Santos, Emeline Cros, John R Mackey, Charles Dumontet

Journal:

BMC Pharmacology

Year:

2004

Language:

english

File:

PDF, 1.08 MB

english, 2004

17

Das Letzigrundstadion in Zürich

Carlo Galmarini, Martin Schollmayer, Martin Mensinger

Journal:

Year:

2008

Language:

german

File:

PDF, 1.02 MB

german, 2008

18

Gemcitabine resistance due to deoxycytidine kinase deficiency can be reverted by fruitfly deoxynucleoside kinase, DmdNK, in human uterine sarcoma cells

Lars Petter Jordheim, Carlos M. Galmarini, Charles Dumontet

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2006

Language:

english

File:

PDF, 277 KB

english, 2006

19

Synthesis and antiproliferative evaluation of pyrazolo[1,5-a]-1,3,5-triazine myoseverin derivatives

Florence Popowycz, Cédric Schneider, Salvatore DeBonis, Dimitrios A. Skoufias, Frank Kozielski, Carlos M. Galmarini, Benoît Joseph

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 586 KB

english, 2009

20

CP-4055 and CP-4126 are active in ara-C and gemcitabine-resistant lymphoma cell lines

Carlos M. Galmarini, Finn Myhren, Marit L. Sandvold

Journal:

British Journal of Haematology

Year:

2009

Language:

english

File:

PDF, 118 KB

english, 2009

21

Heterogeneous Distribution of Tumor Blood Supply Affects the Response to Chemotherapy in Patients with Head and Neck Cancer

FELIPE C. GALMARINI, CARLOS M. GALMARINI, MARÍA I. SARCHI, JORGE ABULAFIA, DARÍO GALMARINI

Journal:

Microcirculation

Year:

2000

Language:

english

File:

PDF, 766 KB

english, 2000

22

Frameshift mutation in the Dok1 gene in chronic lymphocytic leukemia

Lee, Sanghoon, Roy, François, Galmarini, Carlos M, Accardi, Rosita, Michelon, Jocelyne, Viller, Alexandra, Cros, Emeline, Dumontet, Charles, Sylla, Bakary S

Journal:

Year:

2004

Language:

english

File:

PDF, 495 KB

english, 2004

23

F-ara-AMP is a substrate of cytoplasmic 5′-nucleotidase II (cN-II): HPLC and NMR studies of enzymatic dephosphorylation

Jordheim, Lars P., Cros, Emeline, Galmarini, Carlos M., Dumontet, Charles, Bretonnet, Anne-Sophie, Krimm, Isabelle, Lancelin, Jean-Marc, Gagnieu, Marie-Claude

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2006

Language:

english

File:

PDF, 262 KB

english, 2006

24

In vitro susceptibility of CD4+ and CD8+ T cell subsets to fludarabine

Romina Gamberale, Carlos M. Galmarini, Paula Fernández-Calotti, Lars Jordheim, Julio Sánchez-Avalos, Charles Dumontet, Jorge Geffner, Mirta Giordano

Journal:

Biochemical Pharmacology

Year:

2003

Language:

english

File:

PDF, 196 KB

english, 2003

25

Modulation of the human equilibrative nucleoside transporter1 (hENT1) activity by IL-4 and PMA in B cells from chronic lymphocytic leukemia

Paula Fernández Calotti, Carlos María Galmarini, Cristian Cañones, Romina Gamberale, Daniel Saénz, Julio Sánchez Avalos, Mónica Chianelli, Ruth Rosenstein, Mirta Giordano

Journal:

Biochemical Pharmacology

Year:

2008

Language:

english

File:

PDF, 576 KB

english, 2008

26

XPF-Dependent DNA Breaks and RNA Polymerase II Arrest Induced by Antitumor DNA Interstrand Crosslinking-Mimetic Alkaloids

Sascha Feuerhahn, Christophe Giraudon, Marta Martínez-Díez, Juan A. Bueren-Calabuig, Carlos M. Galmarini, Federico Gago, Jean-Marc Egly

Journal:

Chemistry & Biology

Year:

2011

Language:

english

File:

PDF, 1.49 MB

english, 2011

27

p21Cip1 regulates cell–substrate adhesion and interphase microtubule dynamics in untransformed human mammary epithelial cells

Benjamin Pierre Bouchet, Frédérique Fauvet, Gaël Grelier, Carlos María Galmarini, Alain Puisieux

Journal:

European Journal of Cell Biology

Year:

2011

Language:

english

File:

PDF, 1.29 MB

english, 2011

28

βIII-Tubulin is required for interphase microtubule dynamics in untransformed human mammary epithelial cells

Benjamin Pierre Bouchet, Alain Puisieux, Carlos María Galmarini

Journal:

European Journal of Cell Biology

Year:

2011

Language:

english

File:

PDF, 1.02 MB

english, 2011

29

ErbB protein modifications are secondary to severe cell membrane alterations induced by elisidepsin treatment

Tímea Váradi, Janos Roszik, Duarte Lisboa, György Vereb, José Manuel Molina-Guijarro, Carlos M. Galmarini, János Szöllősi, Peter Nagy

Journal:

European Journal of Pharmacology

Year:

2011

Language:

english

File:

PDF, 1.63 MB

english, 2011

30

Influence of p53 and p21WAF1 expression on sensitivity of cancer cells to cladribine

Carlos Marı́a Galmarini, Nathalie Voorzanger, Nicole Falette, Lars Jordheim, Emeline Cros, Alain Puisieux, Charles Dumontet

Journal:

Biochemical Pharmacology

Year:

2003

Language:

english

File:

PDF, 299 KB

english, 2003

31

P-glycoprotein expression by cancer cells affects cell cytotoxicity and cell-cycle perturbations induced by six chemotherapeutic drugs

Carlos M. Galmarini

Journal:

Journal of Experimental Therapeutics and Oncology

Year:

2002

Language:

english

File:

PDF, 361 KB

english, 2002

32

Nucleoside analogues and nucleobases in cancer treatment

Carlos M Galmarini, John R Mackey, Charles Dumontet

Journal:

The Lancet Oncology

Year:

2002

Language:

english

File:

PDF, 1.10 MB

english, 2002

33

The cytotoxic activity of Aplidin in chronic lymphocytic leukemia (CLL) is mediated by a direct effect on leukemic cells and an indirect effect on monocyte-derived cells

Pablo E. Morande, Samanta R. Zanetti, Mercedes Borge, Paula Nannini, Carolina Jancic, Raimundo F. Bezares, Alicia Bitsmans, Miguel González, Andrea L. Rodríguez, Carlos M. Galmarini, Romina Gamberale,

Journal:

Investigational New Drugs

Year:

2012

Language:

english

File:

PDF, 529 KB

english, 2012

34

Pyrimidine nucleoside analogs in cancer treatment

Galmarini, Carlos M, Jordheim, Lars, Dumontet, Charles

Journal:

Expert Review of Anticancer Therapy

Year:

2003

Language:

english

File:

PDF, 166 KB

english, 2003

35

Irvalec Inserts Into the Plasma Membrane Causing Rapid Loss of Integrity and Necrotic Cell Death in Tumor Cells

Macias, Alvaro, Molina-Guijarro, Jose M., David, Miren, Moreno, Cristina, Alicia, de la Cruz, Prieto, Angela, Gonzalez, Teresa, Galmarini, Carlos M., Valenzuela, Carmen

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 49 KB

english, 2012

36

Indolobenzazepin-7-ones and 6-, 8-, and 9-Membered Ring Derivatives as Tubulin Polymerization Inhibitors: Synthesis and Structure−Activity Relationship Studies

Putey, Aurélien, Popowycz, Florence, Do, Quoc-Tuan, Bernard, Philippe, Talapatra, Sandeep K., Kozielski, Frank, Galmarini, Carlos M., Joseph, Benoît

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 3.25 MB

english, 2009

37

Concomitant resistance and early-breast cancer: should we change treatment strategies?

Galmarini, Carlos M., Tredan, Olivier, Galmarini, Felipe C.

Journal:

Cancer and Metastasis Reviews

Year:

2014

Language:

english

File:

PDF, 556 KB

english, 2014

38

Intraarterial Association of CIS-Platinum and Bleomycin in Head and Neck Cancer

Galmarini, Felipe C., Yoel, José, Nakasone, Juan, Molina, Carlos Maria Coni

Journal:

Auris Nasus Larynx

Year:

1985

Language:

english

File:

PDF, 1.68 MB

english, 1985

39

Nibrin is a marker of clinical outcome in patients with advanced serous ovarian cancer treated in the phase III OVA-301 trial

Monk, Bradley J., Kaye, Stanley B., Poveda, Andrés, Herzog, Thomas J., Aracil, Miguel, Nieto, Antonio, Badri, Nadia, Parekh, Trilok V., Tanović, Adnan, Galmarini, Carlos M.

Journal:

Gynecologic Oncology

Year:

2014

Language:

english

File:

PDF, 362 KB

english, 2014

40

Role of IMP-SELECTIVE 5′-NUCLEOTIDASE (cN-II) in HEMATOLOGICAL MALIGNANCIES

Galmarini, Carlos M., Jordheim, Lars, Dumontet, Charles

Journal:

Leukemia and Lymphoma

Year:

2003

Language:

english

File:

PDF, 175 KB

english, 2003

41

Problems Related to Resistance to Cytarabine in Acute Myeloid Leukemia

Cros, Emeline, Jordheim, Lars, Dumontet, Charles, Galmarini, Carlos M

Journal:

Leukemia and Lymphoma

Year:

2004

Language:

english

File:

PDF, 267 KB

english, 2004

42

Comparison of in vitro and in vivo biological effects of trabectedin, lurbinectedin (PM01183) and Zalypsis® (PM00104)

Romano, Michela, Frapolli, Roberta, Zangarini, Monique, Bello, Ezia, Porcu, Luca, Galmarini, Carlos M., García-Fernández, Luis F., Cuevas, Carmen, Allavena, Paola, Erba, Eugenio, D'Incalci, Maurizio

Journal:

International Journal of Cancer

Year:

2013

Language:

english

File:

PDF, 520 KB

english, 2013

43

Inhibitory effects of marine-derived DNA-binding anti-tumour tetrahydroisoquinolines on the Fanconi anaemia pathway

Martínez, Sandra, Pérez, Laura, Galmarini, Carlos M, Aracil, Miguel, Tercero, Juan C, Gago, Federico, Albella, Beatriz, Bueren, Juan A

Journal:

British Journal of Pharmacology

Year:

2013

Language:

english

File:

PDF, 892 KB

english, 2013

44

Survivorship in untreated breast cancer patients

Galmarini, Carlos M., Tredan, Olivier, Galmarini, Felipe C.

Journal:

Medical Oncology

Year:

2015

Language:

english

File:

PDF, 196 KB

english, 2015

45

Substrate cycles and drug resistance to 1-beta-D-arabinofuranosylcytosine (araC)

Fernandez-Calotti, Paula, Jordheim, Lars Petter, Giordano, Mirta, Dumontet, Charles, Galmarini, Carlos Maria

Journal:

Leukemia and Lymphoma

Year:

2005

Language:

english

File:

PDF, 211 KB

english, 2005

46

CD8 Expression in a Case of Chronic Lymphocytic Leukemia with Trisomy 12

Bayo Hanza, Mar&iacute, a Carolina, Palacios, Mar&iacute, a Fernanda, Dourisboure, Ricardo, Slavutsky, Irma, Chena, Christian, Galmarini, Carlos, Sarmiento, Marcela, de Bracco, Mar&iacute, a M.E., Scolni

Journal:

Acta Haematologica

Year:

1999

Language:

english

File:

PDF, 370 KB

english, 1999

47

The Activity of the Lipophilic Nucleoside Derivatives Elacytarabine and CP-4126 in a Panel of Tumor Cell Lines Resistant to Nucleoside Analogues

Sandvold, Marit Liland, Galmarini, Carlos, Myhren, Finn, Peters, Godefridus

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2010

Language:

english

File:

PDF, 134 KB

english, 2010

48

Unique features of trabectedin mechanism of action

Larsen, Annette K., Galmarini, Carlos M., D’Incalci, Maurizio

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 727 KB

english, 2016

49

Weekly administration of paclitaxel induces long-term aneugenicity in nude mice

Galmarini, Carlos M., Bouchet, Benjamin P., Falette, Nicole, Vila, Liliana, Lamblot, Christelle, Audoynaud, Carole, Bertholon, Jacques, Puisieux, Alain

Journal:

Cancer Biology & Therapy

Year:

2007

Language:

english

File:

PDF, 1.08 MB

english, 2007

50

Recent Developments to Improve the Efficacy of Cytotoxic Nucleoside Analogues

Jordheim, Lars, Galmarini, Carlos, Dumontet, Charles

Journal:

Recent Patents on Anti-Cancer Drug Discovery

Year:

2006

Language:

english

File:

PDF, 55 KB

english, 2006